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Mould allergy – Immune system and chronic fungal infections

Mould allergy! Attention! Risk!

Moulds grow in humid places. Black spots in the shower, behind the bedroom closet or under rubber seals are almost unmistakable signs of fungal moulds They can spread through the air in the form of spores and are small enough they get to the nose and lungs when inhaled. Some people who had developed sensitisation – allergy can react and develop symptoms:runny nose, itchy eyes, sneezing and even an asthma attack. Some species of mould also release toxins and may be responsible for other symptoms like headaches, fatigue. Some moulds don’t cause any harm (if there is no allergic sensitisation to them). There are tests that help to diagnose allergy to moulds on one hand and environmental tests to determine if the apartment or house is contaminated with dangerous species of fungus and needs special cleaning by professionals.

Mould is everywhere even in Space in the International Space Station

Mould grows in units called mycelium and reproduce through the formation of spores. Airborne, spores can trigger allergic reactions in sensitised individuals.

In the UK in the outdoor can be found in late winter, and peaking in late summer to autumn (August to November). In warmer climates, mould spores may be found throughout the year.

While indoor moulds can be found all the year round. Indoor mould levels are higher when outdoor mould levels are higher. Therefore, a common source of indoor mould is from the outside environment, or from other indoor mould contamination.

The key element in decreasing exposure is humidity control alongside with preventing mould growth in warm conditions on surfaces rich in nutrients  – wet wood.

London Allergy and Immunology Centre offers consultations with allergy and immunology specialists, who perform specific IgE blood tests or skin prick tests when mould allergy is suspected.

Our Immunology, dermatology and ENT specialists can help to diagnose and treat cases of chronic fungal infection of skin and mucosa.

It is known that some species of mould can have toxic effects.  Especially people may notice general non-allergic symptoms (headache etc) in damp dwellings or after flooding or leak, that go away completely when they stay at their friends or in a hotel and return on re-exposure and usually is experienced by other members of the family.

In these situations identifying location of mould and effective remediation with anti-fungal spays and cleaning solutions can be beneficial.

Interstitial lung disease due to domestic moulds

Pneumopathie interstitielle  diffuse secondaire aux moisissures domestiques Interstitial lung disease due to domestic moulds A.-L. Blanc a ,  ,  , L. Delhaes b , M.-C. Copin c , B. Stach d , J.-B …
Allergy Blog Allergy News Information for Patients GPs and Health Professionals ‎>‎ Interstitial lung disease due to domestic moulds

Protexo novel treatment for allergic asthma – new word in allergen avoidance

… achieve clinically significant allergen avoidance for people allergic to indoor allergens. house dust mites, mould, animals In our clinic you can get an assessment of your condition for suitability to this …
Protexo novel treatment for allergic asthma – new word in allergen avoidance

Online Publication – Nov 2011.pdf

337k — on page Protexo novel treatment for allergic asthma – new word in allergen avoidance
Protexo novel treatment for allergic asthma – new word in allergen avoidance ‎>‎ Online Publication – Nov 2011.pdf

Mouldy home environment in early life is associated with an increased risk of asthma

Meta-analysis of mould and dampness exposure on asthma and allergy in eight European birth cohorts: an ENRIECO initiative C. G. Tischer 1, C. Hohmann 2, E. Thiering 1, O …
Allergy Blog Allergy News Information for Patients GPs and Health Professionals ‎>‎ Mouldy home environment in early life is associated with an increased risk of asthma

Dustborne Alternaria alternata antigens in U.S. homes: Results from the National Survey of Lead and Allergens in Housing
Päivi M. Salo, PhD,1 Ming Yin, PhD,2 Samuel J. Arbes, Jr., DDS, MPH, PhD,1 Richard D. Cohn, PhD,2 Michelle Sever, BS,1 Michael Muilenberg, MS,3Harriet A. Burge, PhD,3* Stephanie J. London, MD, DrPH,1 and Darryl C. Zeldin, MD1

J Allergy Clin Immunol. 2005 September; 116(3): 623–629.
doi:  10.1016/j.jaci.2005.05.030

The role of fungi in diseases of the nose and sinuses

Schimmelpilze: Achtung Allergiegefahr!
Schimmelpilze gedeihen dort, wo es feucht ist. Schwarze Flecken in der Dusche, hinter dem Schlafzimmerschrank oder unter Gummidichtungen stellen nahezu untrügliche Anzeichen dar. Das Hinterhältige an
den Schimmelpilzen sind die Sporen. Sie verbreiten sich über die Luft und gelangen so in die Atemwege. Einige Menschen reagieren darauf mit einer Allergie. So vermeiden Sie Schimmel in der Wohnung


Histoplasmosis is a disease caused by the fungus Histoplasma capsulatum.  The fungus lives in the environment, usually in association with large amounts of bird or bat droppings. Lung infection can occur after a person inhales airborne, microscopic fungal spores from the environment; however, many people who inhale the spores do not get sick.

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