Being overweight increases susceptibility to indoor pollutants among urban children with asthma
Posted: 23rd July 2013 | Posted by AdminMR
Being overweight increases susceptibility to indoor pollutants among urban children with asthma
Background Both being overweight and exposure to indoor pollutants, which have been associated with worse health of asthmatic patients, are common in urban minority populations. Whether being overweight is a risk factor for the effects of indoor pollutant exposure on asthma health is unknown.
Overweight or obese participants also had more asthma symptoms associated with nitrogen dioxide (NO2) exposure than normal-weight participants, although this was not observed across all types of asthma symptoms. Weight did not affect the relationship between exposure to coarse particulate matter measuring between 2.5 and 10 μm in diameter and asthma symptoms. Relationships between indoor pollutant exposure and health care use, lung function, or pulmonary inflammation did not differ by weight. Conclusion Being overweight or obese can increase susceptibility to indoor PM2.5 and NO2 in urban children with asthma. Interventions aimed at weight loss might reduce asthma symptom responses to PM2.5 and NO2, and interventions aimed at reducing indoor pollutant levels might be particularly beneficial in overweight children. Kim D. Lu, Patrick N. Breysse, Gregory B. Diette, Jean Curtin-Brosnan, Charles Aloe, D’Ann L. Williams, Roger D. Peng, Meredith C. McCormack, Elizabeth C. Matsui Being overweight increases susceptibility to indoor pollutants among urban children with asthma The Journal of Allergy and Clinical Immunology – April 2013 (Vol. 131, Issue 4, Pages 1017-1023.e3, DOI: 10.1016/j.jaci.2012.12.1570) Full text: http://www.jacionline.org/article/S0091-6749(13)00006-7/fulltext