Being overweight increases susceptibility to indoor pollutants among urban children with asthma
23rd July 2013
Being overweight increases susceptibility to indoor pollutants among urban children with asthma
Background Both being overweight and exposure to indoor pollutants, which have been associated with worse health of asthmatic patients, are common in urban minority populations. Whether being overweight is a risk factor for the effects of indoor pollutant exposure on asthma health is unknown.
Overweight or obese participants also had more asthma symptoms associated with nitrogen dioxide (NO2) exposure than normal-weight participants, although this was not observed across all types of asthma symptoms. Weight did not affect the relationship between exposure to coarse particulate matter measuring between 2.5 and 10 μm in diameter and asthma symptoms. Relationships between indoor pollutant exposure and health care use, lung function, or pulmonary inflammation did not differ by weight. Conclusion Being overweight or obese can increase susceptibility to indoor PM2.5 and NO2 in urban children with asthma. Interventions aimed at weight loss might reduce asthma symptom responses to PM2.5 and NO2, and interventions aimed at reducing indoor pollutant levels might be particularly beneficial in overweight children. Kim D. Lu, Patrick N. Breysse, Gregory B. Diette, Jean Curtin-Brosnan, Charles Aloe, D’Ann L. Williams, Roger D. Peng, Meredith C. McCormack, Elizabeth C. Matsui Being overweight increases susceptibility to indoor pollutants among urban children with asthma The Journal of Allergy and Clinical Immunology – April 2013 (Vol. 131, Issue 4, Pages 1017-1023.e3, DOI: 10.1016/j.jaci.2012.12.1570)
Full text: http://www.jacionline.org/article/S0091-6749(13)00006-7/fulltext
Cholinergic Urticaria Hives and Treatment
23rd July 2013
CU may be separated into 4 subtypes: CU with poral closure, CU with obtained general hypohidrosis, CU with perspiration sensitivity, and idiopathic CU.
Cholinergic urticaria patches appear rather quickly, usually within a few moments after the start perspiration, and they last from a half-hour to an time or more, with a mean timeframe of about 80 moments.
Cholinergic urticaria indicators are properly unpleasant to cause many people to change their styles of action to prevent problems.
Cholinergic urticaria indicators seem to follow any stimulus to perspiration. A crucial point in cholinergic urticaria is not the actual heat range of the epidermis, the normal epidermis heat range, or even the primary heat range, but it is an increase or a loss of the heavy regular heat range.
Sublingual Immunotherapy in London UK for adults and children
23rd July 2013
Sublingual Immunotherapy
Could it be that those with allergic rhinitis (hay fever) and childhood nasal allergies can finally get a break from their allergies and their allergy shots? Sublingual immunotherapy (SLIT) is a highly effective, easy-to-administer option for chronic allergy and asthma sufferers children and adults.
What Are Allergy Drops?
Sublingual immunotherapy is simply a less invasive way of administering the very same antigen formulas used in allergy shots (subcutaneous immunotherapy) for nearly a century. Allergy shots (subcutaneous immunotherapy) work well but it is complicated to get a injection every week in the up-dosing period of the first 8 weeks, especially for children. And the weekly schedule commitment can be a challenge for parents and busy professionals.
How Does Sublingual Immunotherapy Work?
After comprehensive allergy skin testing allergy solution is then administered daily, in the comfort of the patient’s home, in the form of drops placed under the tongue for 2 minutes in the morning or in the evening. No more injections, no more weekly trips to the doctor.
Just like with allergy shots, SLIT works by exposing the patient to gradually increasing quantities of their allergens to build tolerance and desensitize the immune system. Dosage increases during the escalation phase and then stabilizes for a maintenance phase of about three to five years.
Please see more information HERE about the treatment we can offer
Allergy Shots Immunotherapy
23rd July 2013
If you have allergies, you may be wondering if allergy shots are the best treatment for you. After all, getting regular shots isn’t anyone’s idea of fun, but the possibility of being free from your allergy symptoms may be worth it.
Who Can Be Treated with Shots?
Who Should Be Giving Allergy Shots?
How Do Allergy Shots Work?
When Will I Feel Better?
When Should Allergy Shots be Stopped?
What Are the Possible Reactions?
Feel Better. Live Better.
AAAAI Brochure Tips to Remember
Immunotherapy for hayfever
23rd July 2013
Grass pollen immunotherapy for hayfever is associated with increases in local nasal but not peripheral Th1 : Th2 cytokine ratios
Petra A Wachholz, Kayhan T Nouri-Aria, Duncan R Wilson, Samantha M Walker, Adrienne Verhoef, Stephen J Till, and Stephen R Durham
Grass pollen immunotherapy is the only treatment for hayfever that is both effective and confers long-term benefit. Immunotherapy may act by altering the local nasal mucosal T helper type 2 (Th2) to type 1 (Th1) cytokine balance either by down-regulation and/or immune deviation of T-lymphocyte responses. There is controversy as to whether these changes are detectable in peripheral blood. We therefore examined both local nasal and peripheral T-cell responses to allergen exposure in the same subjects before and after immunotherapy. In a double-blind trial of grass pollen immunotherapy, nasal biopsies were obtained at baseline and during the peak pollen season following 2 years of immunotherapy.
Hay fever warning as pollen level surge expected this summer
17th May 2013
Professor Roy Kennedy, one of Britain’s leading hay fever experts, said levels would soar in what could be the most sudden pollen surge since 1962.
Hay fever – an allergic reaction to pollen – affects around one in five people in the UK.
As sufferers prepare for the toughest summer in decades, we round up everything you need to know about hay fever and the best ways to beat it:
The basics
Hay fever is an allergic reaction to pollen; the fine powder released by plants as part of their reproductive cycle.
Pollen contains proteins which can cause the nose, eyes, throat and sinuses to become swollen, irritated and inflamed.
Read more:
1,3 and John Donnie A. Ramos2,3